Protein profile

KP13_04241

hypothetical protein

Genome: KpKP13

Gene: AHE45473.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GM61
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Amino acids 171
Annotations 0
Features 11
PDB binders 0
Druggability 0.173

Overview

Basic information about this protein and its source genome.

Accession
KP13_04241
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE45473.1
Status
annotated
Amino acids
171
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
73.099
DEG E-value
1.8999999999999998e-90
Localization
Unknown
ColabFold pLDDT
85.91

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.173
Structure A0A0H3GM61
Pocket Pocket 3
P2Rank 0.018
Structure A0A0H3GM61
Pocket Pocket 1
ColabFold model
FPocket 0.098 · Pocket 3
P2Rank 0.019 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 80 / 4744 genomes with a hit
Normalized 0.017

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
1 21 Phobius SIGNAL_PEPTIDE Signal peptide region
5 16 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 15 SignalP_EUK SignalP-noTM SignalP-noTM
22 171 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
17 21 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 27 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
41 154 Pfam PF12883 Protein of unknown function (DUF3828)
41 154 InterPro IPR024289 Domain of unknown function DUF3828
1 4 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 19 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
1 27 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A0H3GM61 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GM61
AlphaFold — — full sequence — Viewing
ColabFold KP13_04241
ColabFold — — full sequence — Loaded