Protein profile

KP13_32004

biofilm-dependent modulation domain-containing protein

Genome: KpKP13

Gene: AHE45608.1 Structure source: AlphaFold + ColabFold UniProt W8UN92
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Amino acids 121
Annotations 1
Features 3
PDB binders 0
Druggability 0.029

Overview

Basic information about this protein and its source genome.

Accession
KP13_32004
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE45608.1
Status
annotated
Amino acids
121
Structure source
AlphaFold + ColabFold
GO
GO:0071468 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
66.43

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.029
Structure W8UN92
Pocket Pocket 2
P2Rank
Structure W8UN92
Pocket No pockets
ColabFold model
FPocket 0.015 · Pocket 9
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0071468 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.

Sequence Features

Domain/signature hits from InterPro and related databases.

3 records
Show feature table
Start End DB Term Name
63 120 Gene3D G3DSA:1.20.5.5260 -
66 115 Pfam PF10798 Biofilm development protein YmgB/AriR
66 115 InterPro IPR024753 Regulatory protein AriR

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_W8UN92 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_W8UN92
AlphaFold — — full sequence — Viewing
ColabFold KP13_32004
ColabFold — — full sequence — Loaded