Protein profile

KP13_03003

hypothetical protein

Genome: KpKP13

Gene: AHE45614.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GU96
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Amino acids 88
Annotations 1
Features 3
PDB binders 0
Druggability 0.077

Overview

Basic information about this protein and its source genome.

Accession
KP13_03003
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE45614.1
Status
annotated
Amino acids
88
Structure source
AlphaFold + ColabFold
GO
GO:0071468 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
88.63

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.077
Structure A0A0H3GU96
Pocket Pocket 2
P2Rank 0.051
Structure A0A0H3GU96
Pocket Pocket 1
ColabFold model
FPocket 0.264 · Pocket 1
P2Rank 0.009 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 50 / 4744 genomes with a hit
Normalized 0.011

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0071468 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.

Sequence Features

Domain/signature hits from InterPro and related databases.

3 records
Show feature table
Start End DB Term Name
25 87 Gene3D G3DSA:1.20.5.5260 -
30 87 Pfam PF10798 Biofilm development protein YmgB/AriR
30 87 InterPro IPR024753 Regulatory protein AriR

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GU96
AlphaFold — — full sequence — Viewing
ColabFold KP13_03003
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.77 0.033