Protein profile

KP13_03258

hypothetical protein

Genome: KpKP13

Gene: AHE45637.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GQ32
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Amino acids 121
Annotations 1
Features 14
PDB binders 0
Druggability 0.428

Overview

Basic information about this protein and its source genome.

Accession
KP13_03258
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE45637.1
Status
annotated
Amino acids
121
Structure source
AlphaFold + ColabFold
GO
GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
53.72

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.428
Structure A0A0H3GQ32
Pocket Pocket 5
P2Rank
Structure A0A0H3GQ32
Pocket No pockets
ColabFold model
FPocket 0.591 · Pocket 2
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 33 / 4744 genomes with a hit
Normalized 0.007

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
25 121 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
3 121 Pfam PF13985 YbgS-like protein
3 121 InterPro IPR020363 Uncharacterised protein family YbgS
1 5 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
25 42 MobiDBLite mobidb-lite consensus disorder prediction
1 24 SignalP_EUK SignalP-noTM SignalP-noTM
6 17 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
20 121 MobiDBLite mobidb-lite consensus disorder prediction
85 100 MobiDBLite mobidb-lite consensus disorder prediction
1 24 Phobius SIGNAL_PEPTIDE Signal peptide region
54 84 MobiDBLite mobidb-lite consensus disorder prediction
18 24 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 24 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
103 121 MobiDBLite mobidb-lite consensus disorder prediction

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GQ32
AlphaFold — — full sequence — Viewing
ColabFold KP13_03258
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.428
7 0.421