Protein profile

KP13_03343

hypothetical protein

Genome: KpKP13

Gene: AHE45722.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GJY1
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Amino acids 87
Annotations 1
Features 10
PDB binders 0
Druggability 0.239

Overview

Basic information about this protein and its source genome.

Accession
KP13_03343
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE45722.1
Status
annotated
Amino acids
87
Structure source
AlphaFold + ColabFold
GO
GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
98.851
DEG E-value
2.2399999999999998e-60
Localization
Cytoplasmic
ColabFold pLDDT
87.16

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.239
Structure A0A0H3GJY1
Pocket Pocket 3
P2Rank
Structure A0A0H3GJY1
Pocket No pockets
ColabFold model
FPocket 0.497 · Pocket 5
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 127 / 4744 genomes with a hit
Normalized 0.027

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
2 87 PANTHER PTHR38036 UPF0250 PROTEIN YBED
2 87 InterPro IPR007454 Uncharacterised protein family UPF0250, YbeD-like
1 87 FunFam G3DSA:3.30.70.260:FF:000002 UPF0250 protein YbeD
7 87 Pfam PF04359 Protein of unknown function (DUF493)
7 87 InterPro IPR007454 Uncharacterised protein family UPF0250, YbeD-like
1 87 SUPERFAMILY SSF117991 YbeD/HP0495-like
1 87 InterPro IPR027471 YbeD-like domain superfamily
1 87 Hamap MF_00659 UPF0250 protein YbeD [ybeD].
1 87 InterPro IPR007454 Uncharacterised protein family UPF0250, YbeD-like
1 87 Gene3D G3DSA:3.30.70.260 -

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GJY1
AlphaFold — — full sequence — Viewing
ColabFold KP13_03343
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.239