Protein profile

KP13_03413

putative lipoprotein

Genome: KpKP13

Gene: AHE45790.1 Structure source: AlphaFold + ColabFold UniProt A0A4S8DE33
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Amino acids 203
Annotations 0
Features 16
PDB binders 0
Druggability 0.221

Overview

Basic information about this protein and its source genome.

Accession
KP13_03413
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE45790.1
Status
annotated
Amino acids
203
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
86.96

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.221
Structure A0A4S8DE33
Pocket Pocket 5
P2Rank
Structure A0A4S8DE33
Pocket No pockets
ColabFold model
FPocket 0.747 · Pocket 2
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 15 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
49 199 SUPERFAMILY SSF141318 TM0957-like
49 199 InterPro IPR036215 TM0957-like superfamily
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
7 25 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 27 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
15 191 Pfam PF10054 Predicted periplasmic lipoprotein (DUF2291)
15 191 InterPro IPR014582 Uncharacterised conserved protein UCP033535, periplasmic lipoprotein
1 21 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
28 203 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 27 SignalP_EUK SignalP-noTM SignalP-noTM
20 27 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
2 202 PIRSF PIRSF033535 UCP033535_plp
2 202 InterPro IPR014582 Uncharacterised conserved protein UCP033535, periplasmic lipoprotein
8 19 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 27 Phobius SIGNAL_PEPTIDE Signal peptide region
1 22 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A4S8DE33
AlphaFold — — full sequence — Viewing
ColabFold KP13_03413
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.221