Protein profile

KP13_03416

putative transposase

Genome: KpKP13

Gene: AHE45793.1 Structure source: ColabFold
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Amino acids 367
Annotations 0
Features 6
PDB binders 0
Druggability 0.599

Overview

Basic information about this protein and its source genome.

Accession
KP13_03416
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE45793.1
Status
annotated
Amino acids
367
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
52.475
DEG E-value
1.6400000000000002e-109
Localization
Cytoplasmic
ColabFold pLDDT
81.23

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.599
Structure CB_KP13_03416
Pocket Pocket 5
P2Rank 0.099
Structure CB_KP13_03416
Pocket Pocket 1
ColabFold model
FPocket 0.599 · Pocket 5
P2Rank 0.099 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 60 / 4744 genomes with a hit
Normalized 0.013

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
56 355 NCBIfam TIGR01784 Rpn family recombination-promoting nuclease/putative transposase
56 355 InterPro IPR010106 Recombination-promoting nuclease RpnA
48 356 PANTHER PTHR34611 -
36 56 MobiDBLite mobidb-lite consensus disorder prediction
55 256 Pfam PF04754 Putative transposase, YhgA-like
55 256 InterPro IPR006842 Transposase (putative), YhgA-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold KP13_03416
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.599
3 0.566
14 0.323

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.85 0.09
2 2.04 0.045
3 1.54 0.023
4 1.32 0.015
5 0.83 0.003