Protein profile

KP13_03596

Outer membrane protein C

Genome: KpKP13

Gene: AHE45939.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GP71
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Amino acids 381
Annotations 0
Features 12
PDB binders 0
Druggability 0.159

Overview

Basic information about this protein and its source genome.

Accession
KP13_03596
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE45939.1
Status
annotated
Amino acids
381
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
91.99

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.159
Structure A0A0H3GP71
Pocket Pocket 15
P2Rank 0.939
Structure A0A0H3GP71
Pocket Pocket 1
ColabFold model
FPocket 0.405 · Pocket 18
P2Rank 0.924 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 69 / 4744 genomes with a hit
Normalized 0.015

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
1 6 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
44 381 SUPERFAMILY SSF56935 Porins
26 381 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
19 25 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
7 18 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 25 Phobius SIGNAL_PEPTIDE Signal peptide region
42 381 Gene3D G3DSA:2.40.160.10 Porin
42 381 InterPro IPR023614 Porin domain superfamily
1 25 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
1 17 SignalP_EUK SignalP-noTM SignalP-noTM
6 381 PANTHER PTHR34501 PROTEIN YDDL-RELATED
1 25 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GP71
AlphaFold — — full sequence — Viewing
ColabFold KP13_03596
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 21.21 0.867
2 4.57 0.197
3 2.65 0.078
4 2.26 0.056
5 1.64 0.027