Protein profile

KP13_02051

Glyoxalase/bleomycin resistance domain-containing protein

Genome: KpKP13

Gene: AHE46054.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GSM4
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Amino acids 121
Annotations 0
Features 10
PDB binders 0
Druggability 0.078

Overview

Basic information about this protein and its source genome.

Accession
KP13_02051
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46054.1
Status
annotated
Amino acids
121
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
96.47

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.078
Structure A0A0H3GSM4
Pocket Pocket 7
P2Rank 0.071
Structure A0A0H3GSM4
Pocket Pocket 1
ColabFold model
FPocket 0.398 · Pocket 1
P2Rank 0.076 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 43 / 4744 genomes with a hit
Normalized 0.009

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
5 119 CDD cd07247 SgaA_N_like
4 120 ProSiteProfiles PS51819 Vicinal oxygen chelate (VOC) domain profile.
4 120 InterPro IPR037523 Vicinal oxygen chelate (VOC) domain
5 115 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
5 115 InterPro IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain
1 121 Gene3D G3DSA:3.10.180.10 -
1 121 InterPro IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
2 121 PANTHER PTHR33993 GLYOXALASE-RELATED
2 120 SUPERFAMILY SSF54593 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
2 120 InterPro IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GSM4
AlphaFold — — full sequence — Viewing
ColabFold KP13_02051
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.93 0.094