Protein profile

KP13_02097

hypothetical protein

Genome: KpKP13

Gene: AHE46097.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GNB8
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Amino acids 368
Annotations 0
Features 13
PDB binders 0
Druggability 0.336

Overview

Basic information about this protein and its source genome.

Accession
KP13_02097
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46097.1
Status
annotated
Amino acids
368
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
90.47

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.336
Structure A0A0H3GNB8
Pocket Pocket 5
P2Rank 0.714
Structure A0A0H3GNB8
Pocket Pocket 1
ColabFold model
FPocket 0.279 · Pocket 6
P2Rank 0.683 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 96 / 4744 genomes with a hit
Normalized 0.02

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
22 26 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 26 Phobius SIGNAL_PEPTIDE Signal peptide region
53 367 Pfam PF07759 Protein of unknown function (DUF1615)
53 367 InterPro IPR011673 Protein of unknown function DUF1615
1 24 SignalP_EUK SignalP-noTM SignalP-noTM
1 28 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
11 21 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 10 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 24 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
1 23 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
196 276 SUPERFAMILY SSF54511 GFP-like
196 276 InterPro IPR009017 Green fluorescent protein
27 368 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GNB8
AlphaFold — — full sequence — Viewing
ColabFold KP13_02097
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.336

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 14.87 0.737
2 4.68 0.205
3 3.67 0.139
4 1.57 0.024
5 1.49 0.021