Protein profile

KP13_02128

hypothetical protein

Genome: KpKP13

Gene: AHE46128.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GNU9
Export view
Amino acids 841
Annotations 0
Features 13
PDB binders 0
Druggability 0.7

Overview

Basic information about this protein and its source genome.

Accession
KP13_02128
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46128.1
Status
annotated
Amino acids
841
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
85.05

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.7
Structure A0A0H3GNU9
Pocket Pocket 4
P2Rank 0.304
Structure A0A0H3GNU9
Pocket Pocket 1
ColabFold model
FPocket 0.875 · Pocket 1
P2Rank 0.379 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 22 / 4744 genomes with a hit
Normalized 0.005

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
23 30 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 29 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
14 22 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 30 Phobius SIGNAL_PEPTIDE Signal peptide region
283 350 Pfam PF16967 E-set like domain
283 350 InterPro IPR032636 Pilus assembly protein, E-set like domain
749 810 SUPERFAMILY SSF49464 Carboxypeptidase regulatory domain-like
749 810 InterPro IPR008969 Carboxypeptidase-like, regulatory domain superfamily
732 824 Pfam PF15976 CS1-pili formation C-terminal
732 824 InterPro IPR031917 Pilus assembly protein, C-terminal domain
1 13 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 30 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
31 841 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GNU9
AlphaFold — — full sequence — Viewing
ColabFold KP13_02128
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.7
75 0.365
18 0.301

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 5.11 0.234
2 3.66 0.138