Protein profile

KP13_02895

Tetratricopeptide repeat-containing protein

Genome: KpKP13

Gene: AHE46171.1 Structure source: AlphaFold + ColabFold UniProt A0A6A8EM01
Export view
Amino acids 525
Annotations 1
Features 5
PDB binders 0
Druggability 0.255

Overview

Basic information about this protein and its source genome.

Accession
KP13_02895
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46171.1
Status
annotated
Amino acids
525
Structure source
AlphaFold + ColabFold
GO
GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
86.8

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.255
Structure A0A6A8EM01
Pocket Pocket 55
P2Rank 0.895
Structure A0A6A8EM01
Pocket Pocket 1
ColabFold model
FPocket 0.306 · Pocket 20
P2Rank 0.841 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

5 records
Show feature table
Start End DB Term Name
206 468 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
206 468 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
511 525 Coils Coil Coil
243 378 SUPERFAMILY SSF48452 TPR-like
243 378 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A6A8EM01
AlphaFold — — full sequence — Viewing
ColabFold KP13_02895
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
55 0.255

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 18.93 0.832
2 4.76 0.21
3 2.57 0.073
4 1.57 0.024
5 0.97 0.005