Protein profile

KP13_02928

putative glutamine amidotransferase

Genome: KpKP13

Gene: AHE46202.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GN31
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Amino acids 255
Annotations 0
Features 10
PDB binders 0
Druggability 0.303

Overview

Basic information about this protein and its source genome.

Accession
KP13_02928
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46202.1
Status
annotated
Amino acids
255
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
46.85
DEG E-value
1.05e-85
Localization
Cytoplasmic
ColabFold pLDDT
89.5

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.303
Structure A0A0H3GN31
Pocket Pocket 4
P2Rank 0.098
Structure A0A0H3GN31
Pocket Pocket 1
ColabFold model
FPocket 0.323 · Pocket 9
P2Rank 0.239 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 151 / 4744 genomes with a hit
Normalized 0.032

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
2 255 ProSiteProfiles PS51278 Glutamine amidotransferase type 2 domain profile.
2 255 InterPro IPR017932 Glutamine amidotransferase type 2 domain
1 254 PANTHER PTHR42824 GLUTAMINE AMIDOTRANSFERASE
1 255 Gene3D G3DSA:3.60.20.10 Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
1 255 InterPro IPR029055 Nucleophile aminohydrolases, N-terminal
1 251 CDD cd01908 YafJ
1 252 Pfam PF13230 Glutamine amidotransferases class-II
1 252 InterPro IPR026869 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase EgtC-like
2 253 SUPERFAMILY SSF56235 N-terminal nucleophile aminohydrolases (Ntn hydrolases)
2 253 InterPro IPR029055 Nucleophile aminohydrolases, N-terminal

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GN31
AlphaFold — — full sequence — Viewing
ColabFold KP13_02928
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.303

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.21 0.053
2 1.9 0.038