Protein profile

KP13_01790

Protein rof

Genome: KpKP13

Gene: rof AHE46230.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GS73
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Amino acids 84
Annotations 0
Features 6
PDB binders 0
Druggability 0.048

Overview

Basic information about this protein and its source genome.

Accession
KP13_01790
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
rof AHE46230.1
Status
annotated
Amino acids
84
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
77.86

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.048
Structure A0A0H3GS73
Pocket Pocket 1
P2Rank 0.005
Structure A0A0H3GS73
Pocket Pocket 1
ColabFold model
FPocket 0.485 · Pocket 1
P2Rank 0.069 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 112 / 4744 genomes with a hit
Normalized 0.024

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
7 81 Pfam PF07073 Modulator of Rho-dependent transcription termination (ROF)
7 81 InterPro IPR009778 Modulator of Rho-dependent transcription termination
1 83 SUPERFAMILY SSF101744 Rof/RNase P subunit-like
1 83 InterPro IPR023534 Rof/RNase P-like
8 84 Gene3D G3DSA:2.30.30.400 -
8 84 InterPro IPR038626 Rof-like superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GS73
AlphaFold — — full sequence — Viewing
ColabFold KP13_01790
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer