Protein profile

KP13_01816

Carbohydrate diacid regulator

Genome: KpKP13

Gene: cdaR AHE46256.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GS24
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Amino acids 403
Annotations 0
Features 10
PDB binders 0
Druggability 0.293

Overview

Basic information about this protein and its source genome.

Accession
KP13_01816
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
cdaR AHE46256.1
Status
annotated
Amino acids
403
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
87.44

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.293
Structure A0A0H3GS24
Pocket Pocket 1
P2Rank 0.322
Structure A0A0H3GS24
Pocket Pocket 1
ColabFold model
FPocket 0.597 · Pocket 29
P2Rank 0.465 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 83 / 4744 genomes with a hit
Normalized 0.017

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
163 289 Pfam PF17853 GGDEF-like domain
163 289 InterPro IPR041522 CdaR, GGDEF-like domain
341 398 Pfam PF13556 PucR C-terminal helix-turn-helix domain
341 398 InterPro IPR025736 PucR C-terminal helix-turn-helix domain
24 156 Pfam PF05651 Putative sugar diacid recognition
24 156 InterPro IPR008599 Putative sugar diacid recognition
276 402 Gene3D G3DSA:1.10.10.2840 -
276 402 InterPro IPR042070 PucR C-terminal helix-turn-helix domain superfamily
27 401 PANTHER PTHR33744 CARBOHYDRATE DIACID REGULATOR
276 402 FunFam G3DSA:1.10.10.2840:FF:000001 Carbohydrate diacid transcriptional regulator

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GS24
AlphaFold — — full sequence — Viewing
ColabFold KP13_01816
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.293

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 3.77 0.145