Protein profile

KP13_01963

hypothetical protein

Genome: KpKP13

Gene: AHE46402.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GN33
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Amino acids 84
Annotations 0
Features 17
PDB binders 0
Druggability 0.271

Overview

Basic information about this protein and its source genome.

Accession
KP13_01963
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46402.1
Status
annotated
Amino acids
84
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
88.34

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.271
Structure A0A0H3GN33
Pocket Pocket 2
P2Rank
Structure A0A0H3GN33
Pocket No pockets
ColabFold model
FPocket 0.223 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 84 / 4744 genomes with a hit
Normalized 0.018

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

17 records
Show feature table
Start End DB Term Name
1 29 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
35 81 Pfam PF06004 Bacterial protein of unknown function (DUF903)
35 81 InterPro IPR047807 Lipoprotein YgdI/YgdR-like, SH3-like domain
13 35 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
30 82 SUPERFAMILY SSF50182 Sm-like ribonucleoproteins
30 82 InterPro IPR010920 LSM domain superfamily
1 11 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 31 Phobius SIGNAL_PEPTIDE Signal peptide region
1 32 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
32 84 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
14 81 NCBIfam NF033216 YgdI/YgdR family lipoprotein
14 81 InterPro IPR010305 Lipoprotein YgdI/YgdR-like
24 31 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
12 23 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
28 84 Gene3D G3DSA:2.30.30.100 -
16 81 PANTHER PTHR37011 POT FAMILY PEPTIDE TRANSPORT PROTEIN-RELATED
16 81 InterPro IPR010305 Lipoprotein YgdI/YgdR-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GN33
AlphaFold — — full sequence — Viewing
ColabFold KP13_01963
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.271