Protein profile

KP13_03709

hypothetical protein

Genome: KpKP13

Gene: AHE46550.1 Structure source: Experimental + ColabFold UniProt A0A0H3GLZ1
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Amino acids 88
Annotations 1
Features 7
PDB binders 0
Druggability 0.73

Overview

Basic information about this protein and its source genome.

Accession
KP13_03709
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46550.1
Status
annotated
Amino acids
88
Structure source
Experimental + ColabFold
GO
GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
92.68

Selected Druggability evidence

PDB experimental structure

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.73
Structure 5ZGN
Pocket Pocket 1
P2Rank
Structure 5ZGN
Pocket No pockets
ColabFold model
FPocket 0.883 · Pocket 2
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 24 / 4744 genomes with a hit
Normalized 0.005

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
8 86 Pfam PF08681 Protein of unknown function (DUF1778)
8 86 InterPro IPR014795 Vibrio phage ICP1, Orf50
3 88 Gene3D G3DSA:1.20.5.780 Single helix bin
5 82 SUPERFAMILY SSF47598 Ribbon-helix-helix
5 82 InterPro IPR010985 Ribbon-helix-helix
2 86 PANTHER PTHR35401 COPG FAMILY HELIX-TURN-HELIX PROTEIN-RELATED-RELATED
2 86 InterPro IPR014795 Vibrio phage ICP1, Orf50

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 5ZGN
X-ray 20.00 Å - —
PDBe RCSB PDBj File
Viewing
ColabFold KP13_03709
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
43 0.229

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 6.68 0.339
2 6.37 0.321
3 3.86 0.151
4 3.11 0.105
5 2.7 0.08