Protein profile

KP13_03727

hypothetical protein

Genome: KpKP13

Gene: AHE46568.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GMM4
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Amino acids 293
Annotations 0
Features 7
PDB binders 0
Druggability 0.759

Overview

Basic information about this protein and its source genome.

Accession
KP13_03727
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46568.1
Status
annotated
Amino acids
293
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
94.68

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.759
Structure A0A0H3GMM4
Pocket Pocket 17
P2Rank 0.464
Structure A0A0H3GMM4
Pocket Pocket 1
ColabFold model
FPocket 0.608 · Pocket 22
P2Rank 0.374 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 92 / 4744 genomes with a hit
Normalized 0.019

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
3 123 Pfam PF04463 2-thiouracil desulfurase
3 123 InterPro IPR007553 2-thiouracil desulfurase
166 283 Pfam PF08349 Protein of unknown function (DUF1722)
166 283 InterPro IPR013560 Domain of unknown function DUF1722
5 237 PANTHER PTHR30087 UNCHARACTERIZED
1 292 PIRSF PIRSF037004 UCP037004
1 292 InterPro IPR017087 Uncharacterised conserved protein UCP037004

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GMM4
AlphaFold — — full sequence — Viewing
ColabFold KP13_03727
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
17 0.759
14 0.217

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 7.67 0.406
2 4.65 0.202
3 1.92 0.039