Protein profile

KP13_01197

hypothetical protein

Genome: KpKP13

Gene: AHE46584.1 Structure source: ColabFold
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Amino acids 371
Annotations 0
Features 14
PDB binders 0
Druggability 0.671

Overview

Basic information about this protein and its source genome.

Accession
KP13_01197
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46584.1
Status
annotated
Amino acids
371
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
88.75

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.671
Structure CB_KP13_01197
Pocket Pocket 28
P2Rank 0.848
Structure CB_KP13_01197
Pocket Pocket 1
ColabFold model
FPocket 0.671 · Pocket 28
P2Rank 0.848 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
1 23 SignalP_EUK SignalP-noTM SignalP-noTM
198 327 Pfam PF02698 DUF218 domain
198 327 InterPro IPR003848 Domain of unknown function DUF218
1 5 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
194 305 PANTHER PTHR30336 INNER MEMBRANE PROTEIN, PROBABLE PERMEASE
18 23 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
24 371 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 23 Phobius SIGNAL_PEPTIDE Signal peptide region
6 17 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
162 318 Gene3D G3DSA:3.40.50.620 HUPs
162 318 InterPro IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
1 23 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
197 305 CDD cd06259 YdcF-like
197 305 InterPro IPR003848 Domain of unknown function DUF218

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold KP13_01197
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
28 0.671

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 14.91 0.738
2 3.74 0.143
3 3.29 0.115
4 2.7 0.081
5 1.97 0.042