Protein profile

KP13_01193

hypothetical protein

Genome: KpKP13

Gene: AHE46588.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GHM9
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Amino acids 289
Annotations 0
Features 5
PDB binders 0
Druggability 0.935

Overview

Basic information about this protein and its source genome.

Accession
KP13_01193
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46588.1
Status
annotated
Amino acids
289
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
93.94

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.935
Structure A0A0H3GHM9
Pocket Pocket 4
P2Rank 0.389
Structure A0A0H3GHM9
Pocket Pocket 1
ColabFold model
FPocket 0.933 · Pocket 2
P2Rank 0.488 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 33 / 4744 genomes with a hit
Normalized 0.007

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

5 records
Show feature table
Start End DB Term Name
1 289 PIRSF PIRSF030850 UCP030850
1 289 InterPro IPR011396 Uncharacterised conserved protein UCP030850
181 234 Pfam PF13391 HNH endonuclease
181 234 InterPro IPR003615 HNH nuclease
151 241 Gene3D G3DSA:1.10.30.50 -

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GHM9
AlphaFold — — full sequence — Viewing
ColabFold KP13_01193
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.935

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 6.18 0.308
2 5.11 0.234
3 2.02 0.044
4 1.69 0.029
5 1.59 0.025