Protein profile

KP13_01295

Fructosamine kinase frlD

Genome: KpKP13

Gene: frlD AHE46639.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GLR3
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Amino acids 277
Annotations 0
Features 7
PDB binders 0
Druggability 0.614

Overview

Basic information about this protein and its source genome.

Accession
KP13_01295
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
frlD AHE46639.1
Status
annotated
Amino acids
277
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
96.77

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.614
Structure A0A0H3GLR3
Pocket Pocket 1
P2Rank 0.963
Structure A0A0H3GLR3
Pocket Pocket 1
ColabFold model
FPocket 0.429 · Pocket 3
P2Rank 0.963 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 6 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
1 271 SUPERFAMILY SSF53613 Ribokinase-like
1 271 InterPro IPR029056 Ribokinase-like
2 270 Pfam PF00294 pfkB family carbohydrate kinase
2 270 InterPro IPR011611 Carbohydrate kinase PfkB
1 273 Gene3D G3DSA:3.40.1190.20 -
1 273 InterPro IPR029056 Ribokinase-like
17 270 PANTHER PTHR10584 SUGAR KINASE

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GLR3
AlphaFold — — full sequence — Viewing
ColabFold KP13_01295
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.614
2 0.198
6 0.043
3 0.002

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 47.17 0.963
2 3.02 0.08
3 2.26 0.046