Protein profile

KP13_01292

hypothetical protein

Genome: KpKP13

Gene: AHE46642.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GIC1
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Amino acids 150
Annotations 2
Features 9
PDB binders 0
Druggability 0.424

Overview

Basic information about this protein and its source genome.

Accession
KP13_01292
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46642.1
Status
annotated
Amino acids
150
Structure source
AlphaFold + ColabFold
GO
GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0044010 A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
97.63

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.424
Structure A0A0H3GIC1
Pocket Pocket 2
P2Rank 0.202
Structure A0A0H3GIC1
Pocket Pocket 1
ColabFold model
FPocket 0.305 · Pocket 1
P2Rank 0.194 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 78 / 4744 genomes with a hit
Normalized 0.016

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
  • GO:0044010 A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
1 148 PANTHER PTHR34986 EVOLVED BETA-GALACTOSIDASE SUBUNIT BETA
1 148 InterPro IPR004375 NanQ anomerase/TabA/YiaL family
1 149 NCBIfam TIGR00022 YhcH/YjgK/YiaL family protein
1 149 InterPro IPR004375 NanQ anomerase/TabA/YiaL family
1 147 Pfam PF04074 YhcH/YjgK/YiaL
1 147 InterPro IPR004375 NanQ anomerase/TabA/YiaL family
1 149 SUPERFAMILY SSF51197 Clavaminate synthase-like
1 149 Gene3D G3DSA:2.60.120.370 YhcH/YjgK/YiaL
1 149 InterPro IPR037012 NanQ anomerase/TabA/YiaL superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GIC1
AlphaFold — — full sequence — Viewing
ColabFold KP13_01292
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.424

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 3.06 0.101
2 0.65 0.001