Protein profile

KP13_01262

hypothetical protein

Genome: KpKP13

Gene: AHE46672.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GMG2
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Amino acids 183
Annotations 4
Features 18
PDB binders 0
Druggability 0.522

Overview

Basic information about this protein and its source genome.

Accession
KP13_01262
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46672.1
Status
annotated
Amino acids
183
Structure source
AlphaFold + ColabFold
GO
GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0043022 Binding to a ribosome. GO:0019843 Binding to a ribosomal RNA. GO:1902626 The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
62.963
DEG E-value
9.970000000000001e-65
Localization
Cytoplasmic
ColabFold pLDDT
85.77

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.522
Structure A0A0H3GMG2
Pocket Pocket 2
P2Rank
Structure A0A0H3GMG2
Pocket No pockets
ColabFold model
FPocket 0.207 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 141 / 4744 genomes with a hit
Normalized 0.03

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

4 GO

Gene Ontology (GO)

4
  • GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
  • GO:0043022 Binding to a ribosome.
  • GO:0019843 Binding to a ribosomal RNA.
  • GO:1902626 The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.

Sequence Features

Domain/signature hits from InterPro and related databases.

18 records
Show feature table
Start End DB Term Name
16 180 Hamap MF_00765 UPF0307 protein YjgA [yjgA].
16 180 InterPro IPR006839 Ribosome-associated, YjgA
10 183 PIRSF PIRSF016183 UCP016183
10 183 InterPro IPR006839 Ribosome-associated, YjgA
37 179 SUPERFAMILY SSF158710 PSPTO4464-like
37 179 InterPro IPR023153 PSPTO4464-like domain superfamily
112 183 FunFam G3DSA:1.10.60.30:FF:000002 UPF0307 protein YjgA
37 110 Gene3D G3DSA:1.10.60.30 -
37 110 InterPro IPR023153 PSPTO4464-like domain superfamily
27 176 Pfam PF04751 Protein of unknown function (DUF615)
27 176 InterPro IPR006839 Ribosome-associated, YjgA
112 183 Gene3D G3DSA:1.10.60.30 -
112 183 InterPro IPR023153 PSPTO4464-like domain superfamily
26 177 CDD cd16331 YjgA-like
26 177 InterPro IPR006839 Ribosome-associated, YjgA
2 182 PANTHER PTHR38101 UPF0307 PROTEIN YJGA
2 182 InterPro IPR006839 Ribosome-associated, YjgA
37 110 FunFam G3DSA:1.10.60.30:FF:000001 UPF0307 protein YjgA

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GMG2
AlphaFold — — full sequence — Viewing
ColabFold KP13_01262
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.522
3 0.011
14 0.002
4 0.0