Protein profile

KP13_00467

Chaperone modulatory protein cbpM

Genome: KpKP13

Gene: AHE46799.1 cbpM Structure source: AlphaFold + ColabFold UniProt A0A0H3GHV1
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Amino acids 106
Annotations 0
Features 3
PDB binders 0
Druggability 0.129

Overview

Basic information about this protein and its source genome.

Accession
KP13_00467
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46799.1 cbpM
Status
annotated
Amino acids
106
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
71.0
DEG E-value
6.469999999999999e-48
Localization
Unknown
ColabFold pLDDT
93.03

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.129
Structure A0A0H3GHV1
Pocket Pocket 1
P2Rank
Structure A0A0H3GHV1
Pocket No pockets
ColabFold model
FPocket 0.288 · Pocket 9
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 49 / 4744 genomes with a hit
Normalized 0.01

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

3 records
Show feature table
Start End DB Term Name
6 106 Gene3D G3DSA:1.10.1660.10 -
78 98 Coils Coil Coil
13 97 Pfam PF13591 MerR HTH family regulatory protein

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GHV1
AlphaFold — — full sequence — Viewing
ColabFold KP13_00467
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer