Protein profile

KP13_00459

Protein phnA

Genome: KpKP13

Gene: AHE46807.1 phnA Structure source: AlphaFold + ColabFold UniProt A0AB74GKN7
Export view
Amino acids 92
Annotations 0
Features 9
PDB binders 0
Druggability 0.65

Overview

Basic information about this protein and its source genome.

Accession
KP13_00459
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46807.1 phnA
Status
annotated
Amino acids
92
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
68.478
DEG E-value
2.0199999999999998e-42
Localization
Unknown
ColabFold pLDDT
79.72

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.65
Structure A0AB74GKN7
Pocket Pocket 2
P2Rank
Structure A0AB74GKN7
Pocket No pockets
ColabFold model
FPocket 0.761 · Pocket 2
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 447 / 4744 genomes with a hit
Normalized 0.094

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
23 92 Gene3D G3DSA:2.30.30.40 SH3 Domains
6 92 PANTHER PTHR30305 UNCHARACTERIZED
23 92 FunFam G3DSA:2.30.30.40:FF:000013 Alkylphosphonate utilization protein PhnA
20 91 SUPERFAMILY SSF82057 Prokaryotic SH3-related domain
25 92 Pfam PF03831 PhnA domain
25 92 InterPro IPR013988 Protein YjdM, C-terminal
1 21 Gene3D G3DSA:2.20.25.10 -
1 92 NCBIfam TIGR00686 zinc ribbon domain-containing protein YjdM
1 92 InterPro IPR004624 Protein YjdM

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0AB74GKN7
AlphaFold — — full sequence — Viewing
ColabFold KP13_00459
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.65