Protein profile

KP13_01379

hypothetical protein

Genome: KpKP13

Gene: AHE46920.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GHB8
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Amino acids 231
Annotations 0
Features 7
PDB binders 0
Druggability 0.392

Overview

Basic information about this protein and its source genome.

Accession
KP13_01379
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE46920.1
Status
annotated
Amino acids
231
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
89.35

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.392
Structure A0A0H3GHB8
Pocket Pocket 2
P2Rank 0.512
Structure A0A0H3GHB8
Pocket Pocket 1
ColabFold model
FPocket 0.34 · Pocket 5
P2Rank 0.452 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 64 / 4744 genomes with a hit
Normalized 0.013

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
1 19 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
33 231 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
42 227 Pfam PF07356 Protein of unknown function (DUF1481)
42 227 InterPro IPR010858 Protein of unknown function DUF1481
20 28 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
29 32 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 32 Phobius SIGNAL_PEPTIDE Signal peptide region

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GHB8
AlphaFold — — full sequence — Viewing
ColabFold KP13_01379
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.392

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 7.47 0.392
2 1.88 0.037
3 1.54 0.023