Protein profile

KP13_02695

Acetolactate synthase isozyme 2 small subunit

Genome: KpKP13

Gene: AHE47017.1 ilvM Structure source: AlphaFold + ColabFold UniProt A0A0H3GH19
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Amino acids 85
Annotations 0
Features 4
PDB binders 0
Druggability 0.149

Overview

Basic information about this protein and its source genome.

Accession
KP13_02695
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47017.1 ilvM
Status
annotated
Amino acids
85
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
89.1

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.149
Structure A0A0H3GH19
Pocket Pocket 1
P2Rank
Structure A0A0H3GH19
Pocket No pockets
ColabFold model
FPocket 0.175 · Pocket 7
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 119 / 4744 genomes with a hit
Normalized 0.025

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
2 85 Gene3D G3DSA:3.30.70.260 -
13 73 Pfam PF13710 ACT domain
3 75 SUPERFAMILY SSF55021 ACT-like
3 75 InterPro IPR045865 ACT-like domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A0H3GH19 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GH19
AlphaFold — — full sequence — Viewing
ColabFold KP13_02695
ColabFold — — full sequence — Loaded