Protein profile

KP13_32206

membrane protein insertion efficiency factor

Genome: KpKP13

Gene: AHE47158.1 Structure source: AlphaFold + ColabFold UniProt A6TG07
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Amino acids 86
Annotations 0
Features 10
PDB binders 0
Druggability 0.978

Overview

Basic information about this protein and its source genome.

Accession
KP13_32206
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47158.1
Status
annotated
Amino acids
86
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
95.294
DEG E-value
3.22e-56
Localization
Unknown
ColabFold pLDDT
72.2

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.978
Structure A6TG07
Pocket Pocket 6
P2Rank 0.547
Structure A6TG07
Pocket Pocket 1
ColabFold model
FPocket 0.765 · Pocket 2
P2Rank 0.156 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 1665 / 4744 genomes with a hit
Normalized 0.351

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
9 77 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD].
9 77 InterPro IPR002696 Membrane protein insertion efficiency factor YidD-like
9 76 SMART SM01234 Haemolytic_2
9 76 InterPro IPR002696 Membrane protein insertion efficiency factor YidD-like
11 72 NCBIfam TIGR00278 membrane protein insertion efficiency factor YidD
11 72 InterPro IPR002696 Membrane protein insertion efficiency factor YidD-like
11 76 Pfam PF01809 Putative membrane protein insertion efficiency factor
11 76 InterPro IPR002696 Membrane protein insertion efficiency factor YidD-like
8 78 PANTHER PTHR33383 MEMBRANE PROTEIN INSERTION EFFICIENCY FACTOR-RELATED
8 78 InterPro IPR002696 Membrane protein insertion efficiency factor YidD-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A6TG07
AlphaFold — — full sequence — Viewing
ColabFold KP13_32206
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
6 0.978

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 8.18 0.435