Protein profile

KP13_06780

Regulatory protein rop

Genome: KpKP13

Gene: AHE41792.1 rop Structure source: AlphaFold + ColabFold UniProt A0A4S4RWE7
Export view
Amino acids 63
Annotations 0
Features 15
PDB binders 0
Druggability 0.423

Overview

Basic information about this protein and its source genome.

Accession
KP13_06780
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE41792.1 rop
Status
annotated
Amino acids
63
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
96.44

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.423
Structure A0A4S4RWE7
Pocket Pocket 2
P2Rank
Structure A0A4S4RWE7
Pocket No pockets
ColabFold model
FPocket 0.409 · Pocket 2
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 12 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records
Show feature table
Start End DB Term Name
1 63 Gene3D G3DSA:1.10.287.230 -
30 42 PRINTS PR00835 Regulatory protein Rop signature
30 42 InterPro IPR000769 Regulatory protein Rop
14 29 PRINTS PR00835 Regulatory protein Rop signature
14 29 InterPro IPR000769 Regulatory protein Rop
2 14 PRINTS PR00835 Regulatory protein Rop signature
2 14 InterPro IPR000769 Regulatory protein Rop
42 54 PRINTS PR00835 Regulatory protein Rop signature
42 54 InterPro IPR000769 Regulatory protein Rop
1 57 Pfam PF01815 Rop protein
1 57 InterPro IPR000769 Regulatory protein Rop
1 63 PIRSF PIRSF003229 ROM
1 63 InterPro IPR000769 Regulatory protein Rop
1 58 SUPERFAMILY SSF47380 ROP protein
1 58 InterPro IPR035962 Rop-like superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A4S4RWE7
AlphaFold — — full sequence — Viewing
ColabFold KP13_06780
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.423