Protein profile

KP13_06651

hypothetical protein

Genome: KpKP13

Gene: AHE41866.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H024
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Amino acids 178
Annotations 2
Features 6
PDB binders 0
Druggability 0.199

Overview

Basic information about this protein and its source genome.

Accession
KP13_06651
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE41866.1
Status
annotated
Amino acids
178
Structure source
AlphaFold + ColabFold
GO
GO:0016311 The process of removing one or more phosphoric (ester or anhydride) residues from a molecule. GO:0016791 Catalysis of the hydrolysis of a phosphoric monoester, releasing a phosphate.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
94.1

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.199
Structure A0A0H3H024
Pocket Pocket 2
P2Rank 0.01
Structure A0A0H3H024
Pocket Pocket 1
ColabFold model
FPocket 0.565 · Pocket 6
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 3 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0016311 The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
  • GO:0016791 Catalysis of the hydrolysis of a phosphoric monoester, releasing a phosphate.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
77 126 SUPERFAMILY SSF52799 (Phosphotyrosine protein) phosphatases II
77 126 InterPro IPR029021 Protein-tyrosine phosphatase-like
99 109 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site.
99 109 InterPro IPR016130 Protein-tyrosine phosphatase, active site
38 160 Gene3D G3DSA:3.90.190.10 Protein tyrosine phosphatase superfamily
38 160 InterPro IPR029021 Protein-tyrosine phosphatase-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H024
AlphaFold — — full sequence — Viewing
ColabFold KP13_06651
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer