Overview
Basic information about this protein and its source genome.
- Accession
- KP13_32086
- Gene
- AHE41883.1
- Status
- annotated
- Amino acids
- 991
- Structure source
- AlphaFold + ColabFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Human identity (%)
- 0.0
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- DEG identity (%)
- 0.0
- Localization
- Cytoplasmic
- ColabFold pLDDT
- 61.81
Selected Druggability evidence
AlphaFold / UniProt modelSelected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
No GO or EC annotations are currently loaded for this protein.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 812 | 871 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 44 | 272 | Gene3D | G3DSA:1.10.3210.40 | - |
| 776 | 871 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 422 | 600 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 422 | 440 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 563 | 577 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 792 | 806 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 50 | 356 | Pfam | PF07514 | Putative helicase |
| 50 | 356 | InterPro | IPR011119 | Uncharacterised domain, helicase/relaxase, putative |
| 82 | 279 | SUPERFAMILY | SSF109604 | HD-domain/PDEase-like |
| 468 | 526 | MobiDBLite | mobidb-lite | consensus disorder prediction |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
0 + 2Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
| Entry | Method | Resolution | Chain | Coverage | Links | Status |
|---|---|---|---|---|---|---|
|
AlphaFold
AF_A0AB73VVG7
|
AlphaFold | — | — | full sequence | — | Viewing |
|
ColabFold
KP13_32086
|
ColabFold | — | — | full sequence | — | Loaded |
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 67 | 0.563 |
Pockets (P2RANK)
Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).
| P2RANK | Sticks | Spheres | Surfaces | Score | Probability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|---|
| 1 | 12.97 | 0.67 | ||||||
| 2 | 1.26 | 0.013 | ||||||
| 3 | 1.22 | 0.011 | ||||||
| 4 | 0.86 | 0.003 | ||||||
| 5 | 0.74 | 0.002 |
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 70 | 0.366 | ||||||
| 68 | 0.216 |
Pockets (P2RANK)
Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).
| P2RANK | Sticks | Spheres | Surfaces | Score | Probability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|---|
| 1 | 12.54 | 0.654 | ||||||
| 2 | 7.08 | 0.367 | ||||||
| 3 | 3.29 | 0.115 | ||||||
| 4 | 2.0 | 0.043 | ||||||
| 5 | 1.57 | 0.024 |