Protein profile

KP13_05632

Transcriptional repressor protein, KorB

Genome: KpKP13

Gene: AHE41911.1 Structure source: AlphaFold + ColabFold UniProt A0A7S8H6V3
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Amino acids 312
Annotations 3
Features 8
PDB binders 0
Druggability 0.22

Overview

Basic information about this protein and its source genome.

Accession
KP13_05632
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE41911.1
Status
annotated
Amino acids
312
Structure source
AlphaFold + ColabFold
GO
GO:0005694 A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. GO:0007059 The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. GO:0045881 Any process that activates or increases the frequency, rate or extent of sporulation.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
86.7

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.22
Structure A0A7S8H6V3
Pocket Pocket 25
P2Rank 0.089
Structure A0A7S8H6V3
Pocket Pocket 1
ColabFold model
FPocket 0.591 · Pocket 10
P2Rank 0.035 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 3 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0005694 A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
  • GO:0007059 The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
  • GO:0045881 Any process that activates or increases the frequency, rate or extent of sporulation.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
57 235 PANTHER PTHR33375 CHROMOSOME-PARTITIONING PROTEIN PARB-RELATED
131 224 Gene3D G3DSA:1.10.10.2830 -
132 220 SUPERFAMILY SSF109709 KorB DNA-binding domain-like
290 312 MobiDBLite mobidb-lite consensus disorder prediction
214 239 MobiDBLite mobidb-lite consensus disorder prediction
56 101 CDD cd16387 ParB_N_Srx
58 118 SUPERFAMILY SSF110849 ParB/Sulfiredoxin
58 118 InterPro IPR036086 ParB/Sulfiredoxin superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A7S8H6V3
AlphaFold — — full sequence — Viewing
ColabFold KP13_05632
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
25 0.22

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.59 0.074