Protein profile

KP13_32100

F-type conjugal transfer TraG-like protein

Genome: KpKP13

Gene: AHE41967.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H234
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Amino acids 1204
Annotations 0
Features 19
PDB binders 0
Druggability 0.703

Overview

Basic information about this protein and its source genome.

Accession
KP13_32100
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE41967.1
Status
annotated
Amino acids
1204
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
69.06

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.703
Structure A0A0H3H234
Pocket Pocket 73
P2Rank 0.905
Structure A0A0H3H234
Pocket Pocket 1
ColabFold model
FPocket 0.843 · Pocket 5
P2Rank 0.801 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 2 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

19 records
Show feature table
Start End DB Term Name
395 425 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
423 445 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
376 394 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
34 52 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
888 935 MobiDBLite mobidb-lite consensus disorder prediction
34 51 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
453 1204 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
341 363 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
63 82 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
371 375 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
373 395 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
6 466 Pfam PF07916 TraG-like protein, N-terminal region
6 466 InterPro IPR012931 TraG, N-terminal, Proteobacteria
895 931 MobiDBLite mobidb-lite consensus disorder prediction
53 347 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
426 452 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
348 370 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
1 33 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
92 114 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H234
AlphaFold — — full sequence — Viewing
ColabFold KP13_32100
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
73 0.703
39 0.301

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 35.76 0.954
2 14.83 0.736
3 12.84 0.664
4 4.12 0.166
5 1.47 0.02