Protein profile

KP13_03981

TraG domain-containing protein

Genome: KpKP13

Gene: AHE47173.1 Structure source: ColabFold UniProt A0A1J0QZR0
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Amino acids 1221
Annotations 0
Features 26
PDB binders 0
Druggability 0.958

Overview

Basic information about this protein and its source genome.

Accession
KP13_03981
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47173.1
Status
annotated
Amino acids
1221
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
CytoplasmicMembrane
ColabFold pLDDT
54.19

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.958
Structure CB_KP13_03981
Pocket Pocket 104
P2Rank 0.657
Structure CB_KP13_03981
Pocket Pocket 1
ColabFold model
FPocket 0.958 · Pocket 104
P2Rank 0.657 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

26 records
Show feature table
Start End DB Term Name
7 31 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
32 36 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
425 455 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
900 962 MobiDBLite mobidb-lite consensus disorder prediction
83 361 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
7 29 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1029 1051 MobiDBLite mobidb-lite consensus disorder prediction
392 402 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
8 491 Pfam PF07916 TraG-like protein, N-terminal region
8 491 InterPro IPR012931 TraG, N-terminal, Proteobacteria
403 424 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
456 478 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
990 1065 MobiDBLite mobidb-lite consensus disorder prediction
371 393 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
65 82 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
362 391 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
37 53 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
403 424 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1143 1163 MobiDBLite mobidb-lite consensus disorder prediction
1 6 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
456 478 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1143 1183 MobiDBLite mobidb-lite consensus disorder prediction
730 750 Coils Coil Coil
54 64 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
479 1221 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
65 82 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold KP13_03981
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
104 0.958
114 0.668
110 0.479

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 10.62 0.57
2 10.45 0.562
3 8.13 0.433
4 7.37 0.386
5 6.52 0.33