Protein profile

KP13_03730

putative transposase

Genome: KpKP13

Gene: AHE47185.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H041
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Amino acids 322
Annotations 0
Features 4
PDB binders 0
Druggability 0.074

Overview

Basic information about this protein and its source genome.

Accession
KP13_03730
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47185.1
Status
annotated
Amino acids
322
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Periplasmic
ColabFold pLDDT
88.79

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.074
Structure A0A0H3H041
Pocket Pocket 23
P2Rank 0.091
Structure A0A0H3H041
Pocket Pocket 1
ColabFold model
FPocket 0.321 · Pocket 2
P2Rank 0.098 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 23 / 4744 genomes with a hit
Normalized 0.005

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
17 319 PANTHER PTHR34631 -
24 311 NCBIfam NF033579 IS5 family transposase
34 145 Pfam PF13737 Transposase DDE domain
34 145 InterPro IPR025668 Transposase DDE domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H041
AlphaFold — — full sequence — Viewing
ColabFold KP13_03730
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.31 0.059
2 2.29 0.058
3 1.2 0.011