Protein profile

KP13_32045

Conjugal transfer protein TraD

Genome: KpKP13

Gene: AHE47190.1 Structure source: ColabFold
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Amino acids 478
Annotations 0
Features 7
PDB binders 0
Druggability 0.944

Overview

Basic information about this protein and its source genome.

Accession
KP13_32045
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47190.1
Status
annotated
Amino acids
478
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Extracellular
ColabFold pLDDT
81.4

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.944
Structure CB_KP13_32045
Pocket Pocket 36
P2Rank 0.725
Structure CB_KP13_32045
Pocket Pocket 1
ColabFold model
FPocket 0.944 · Pocket 36
P2Rank 0.725 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 1 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
8 437 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases
8 437 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
197 438 Gene3D G3DSA:3.40.50.300 -
197 438 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
243 424 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain
243 424 InterPro IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain
245 348 CDD cd01127 TrwB_TraG_TraD_VirD4

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold KP13_32045
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
36 0.944
12 0.578
4 0.451

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 10.09 0.543
2 2.4 0.064