Protein profile

KP13_31613

Hemolysin expression-modulating protein

Genome: KpKP13

Gene: AHE47211.1 Structure source: AlphaFold + ColabFold UniProt A0A024HVC9
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Amino acids 84
Annotations 0
Features 6
PDB binders 0
Druggability 0.411

Overview

Basic information about this protein and its source genome.

Accession
KP13_31613
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47211.1
Status
annotated
Amino acids
84
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
45.455
DEG E-value
1.52e-14
Localization
Unknown
ColabFold pLDDT
87.98

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.411
Structure A0A024HVC9
Pocket Pocket 5
P2Rank
Structure A0A024HVC9
Pocket No pockets
ColabFold model
FPocket 0.122 · Pocket 3
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 2 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
5 80 Gene3D G3DSA:1.20.1280.40 HHA
5 80 InterPro IPR036666 HHA superfamily
18 77 Pfam PF05321 Haemolysin expression modulating protein
18 77 InterPro IPR007985 Haemolysin expression modulating, HHA
11 80 SUPERFAMILY SSF68989 Hemolysin expression modulating protein HHA
11 80 InterPro IPR036666 HHA superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A024HVC9
AlphaFold — — full sequence — Viewing
ColabFold KP13_31613
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.411