Protein profile

KP13_03980

F-type conjugal transfer mating pair stabilization protein TraN

Genome: KpKP13

Gene: AHE47253.1 Structure source: AlphaFold + ColabFold UniProt A0A483ZLN9
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Amino acids 1061
Annotations 0
Features 10
PDB binders 0
Druggability 0.925

Overview

Basic information about this protein and its source genome.

Accession
KP13_03980
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47253.1
Status
annotated
Amino acids
1061
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Extracellular
ColabFold pLDDT
65.36

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.925
Structure A0A483ZLN9
Pocket Pocket 56
P2Rank 0.541
Structure A0A483ZLN9
Pocket Pocket 1
ColabFold model
FPocket 0.712 · Pocket 80
P2Rank 0.943 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 4 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
1 5 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
7 29 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
18 23 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 23 Phobius SIGNAL_PEPTIDE Signal peptide region
6 17 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
539 694 Pfam PF06986 Type-1V conjugative transfer system mating pair stabilisation
539 694 InterPro IPR014121 Type-F conjugative transfer system mating-pair stabilisation protein TraN
872 949 Pfam PF06986 Type-1V conjugative transfer system mating pair stabilisation
872 949 InterPro IPR014121 Type-F conjugative transfer system mating-pair stabilisation protein TraN
24 1061 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A483ZLN9
AlphaFold — — full sequence — Viewing
ColabFold KP13_03980
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
85 0.671
83 0.5

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 10.42 0.56
2 5.98 0.294
3 5.09 0.233
4 4.9 0.221
5 4.23 0.173