Protein profile

KP13_32056

F-type conjugative transfer system pilin assembly TraW

Genome: KpKP13

Gene: AHE47255.1 Structure source: AlphaFold + ColabFold UniProt A0A3P2IM47
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Amino acids 453
Annotations 0
Features 10
PDB binders 0
Druggability 0.942

Overview

Basic information about this protein and its source genome.

Accession
KP13_32056
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47255.1
Status
annotated
Amino acids
453
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
69.84

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.942
Structure A0A3P2IM47
Pocket Pocket 32
P2Rank 0.125
Structure A0A3P2IM47
Pocket Pocket 1
ColabFold model
FPocket 0.26 · Pocket 43
P2Rank 0.251 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 1 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
141 227 Pfam PF09673 Type-F conjugative transfer system pilin assembly protein
141 227 InterPro IPR019106 Type-F conjugative transfer system pilin assembly protein TrbC
10 18 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 23 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
437 453 Coils Coil Coil
1 23 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
19 23 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 23 Phobius SIGNAL_PEPTIDE Signal peptide region
1 9 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
24 453 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A3P2IM47
AlphaFold — — full sequence — Viewing
ColabFold KP13_32056
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
32 0.942
53 0.315

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.93 0.039
2 1.82 0.035
3 1.65 0.027
4 1.28 0.013