Protein profile

KP13_03079

F-type conjugal transfer protein TraC

Genome: KpKP13

Gene: AHE47268.1 Structure source: ColabFold UniProt A0ACC7Q2W3
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Amino acids 885
Annotations 0
Features 16
PDB binders 0
Druggability 0.612

Overview

Basic information about this protein and its source genome.

Accession
KP13_03079
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47268.1
Status
annotated
Amino acids
885
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
86.33

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.612
Structure CB_KP13_03079
Pocket Pocket 29
P2Rank 0.772
Structure CB_KP13_03079
Pocket Pocket 1
ColabFold model
FPocket 0.612 · Pocket 29
P2Rank 0.772 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 4 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
10 244 Pfam PF11130 TraC protein
10 244 InterPro IPR025955 Type-IV secretion system protein TraC/Conjugative transfer ATPase
404 796 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases
404 796 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
1 682 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
506 871 Pfam PF19044 TraG P-loop domain
506 871 InterPro IPR043964 TraG, P-loop domain
657 842 Gene3D G3DSA:3.40.50.300 -
657 842 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
416 586 Gene3D G3DSA:3.40.50.300 -
416 586 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
683 702 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
703 885 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
507 869 PANTHER PTHR38467 -
269 418 Pfam PF19357 Family of unknown function (DUF5934)
269 418 InterPro IPR045978 TraC, central domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold KP13_03079
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
29 0.612
2 0.343
15 0.3

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 11.55 0.615
2 6.82 0.349
3 5.46 0.26
4 5.08 0.232
5 4.97 0.225