Protein profile

KP13_03098

putative periplasmic protein

Genome: KpKP13

Gene: AHE47287.1 Structure source: AlphaFold + ColabFold UniProt A0A0J4WV18
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Amino acids 821
Annotations 0
Features 14
PDB binders 0
Druggability 0.376

Overview

Basic information about this protein and its source genome.

Accession
KP13_03098
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47287.1
Status
annotated
Amino acids
821
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
89.22

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.376
Structure A0A0J4WV18
Pocket Pocket 33
P2Rank 0.582
Structure A0A0J4WV18
Pocket Pocket 1
ColabFold model
FPocket 0.329 · Pocket 33
P2Rank 0.734 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
1 37 Phobius SIGNAL_PEPTIDE Signal peptide region
563 719 Pfam PF13750 Bacterial Ig-like domain (group 3)
563 719 InterPro IPR022038 Ig-like domain, bacterial type
38 821 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 18 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 24 SignalP_EUK SignalP-noTM SignalP-noTM
156 282 Pfam PF12245 Bacterial Ig-like domain
156 282 InterPro IPR022038 Ig-like domain, bacterial type
1 37 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 35 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
19 29 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
30 37 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
35 154 Pfam PF13752 Domain of unknown function (DUF4165)
35 154 InterPro IPR025429 Domain of unknown function DUF4165

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0J4WV18
AlphaFold — — full sequence — Viewing
ColabFold KP13_03098
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
33 0.376

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 6.69 0.34
2 4.06 0.163
3 1.99 0.043
4 1.62 0.026