Protein profile

KP13_03114

putative periplasmic protein

Genome: KpKP13

Gene: AHE47300.1 Structure source: AlphaFold + ColabFold UniProt A0A1J0QZK9
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Amino acids 801
Annotations 0
Features 12
PDB binders 0
Druggability 0.286

Overview

Basic information about this protein and its source genome.

Accession
KP13_03114
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47300.1
Status
annotated
Amino acids
801
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
OuterMembrane
ColabFold pLDDT
90.34

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.286
Structure A0A1J0QZK9
Pocket Pocket 40
P2Rank 0.109
Structure A0A1J0QZK9
Pocket Pocket 1
ColabFold model
FPocket 0.325 · Pocket 49
P2Rank 0.422 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
1 6 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
7 18 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
139 263 Pfam PF12245 Bacterial Ig-like domain
139 263 InterPro IPR022038 Ig-like domain, bacterial type
19 22 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
21 137 Pfam PF13752 Domain of unknown function (DUF4165)
21 137 InterPro IPR025429 Domain of unknown function DUF4165
1 22 SignalP_EUK SignalP-noTM SignalP-noTM
544 700 Pfam PF13750 Bacterial Ig-like domain (group 3)
544 700 InterPro IPR022038 Ig-like domain, bacterial type
1 22 Phobius SIGNAL_PEPTIDE Signal peptide region
23 801 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A1J0QZK9
AlphaFold — — full sequence — Viewing
ColabFold KP13_03114
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
40 0.286

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.17 0.051
2 2.15 0.05
3 1.64 0.027
4 1.63 0.027
5 1.45 0.019