Protein profile

KP13_02639

hypothetical protein

Genome: KpKP13

Gene: AHE47373.1 Structure source: AlphaFold + ColabFold UniProt A0A372KU85
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Amino acids 220
Annotations 0
Features 10
PDB binders 0
Druggability 0.07

Overview

Basic information about this protein and its source genome.

Accession
KP13_02639
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47373.1
Status
annotated
Amino acids
220
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
62.7

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.07
Structure A0A372KU85
Pocket Pocket 3
P2Rank
Structure A0A372KU85
Pocket No pockets
ColabFold model
FPocket 0.576 · Pocket 4
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
1 29 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 11 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 29 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
23 29 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
30 194 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
12 22 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
195 213 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
1 29 Phobius SIGNAL_PEPTIDE Signal peptide region
195 212 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
214 220 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A372KU85
AlphaFold — — full sequence — Viewing
ColabFold KP13_02639
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer