Protein profile

KP13_01426

Uroporphyrin-III C/tetrapyrrole

Genome: KpKP13

Gene: AHE47406.1 Structure source: ColabFold
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Amino acids 78
Annotations 1
Features 6
PDB binders 0
Druggability 0.249

Overview

Basic information about this protein and its source genome.

Accession
KP13_01426
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47406.1
Status
annotated
Amino acids
78
Structure source
ColabFold
GO
GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
80.29

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.249
Structure CB_KP13_01426
Pocket Pocket 4
P2Rank 0.035
Structure CB_KP13_01426
Pocket Pocket 1
ColabFold model
FPocket 0.249 · Pocket 4
P2Rank 0.035 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 159 / 4744 genomes with a hit
Normalized 0.034

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
4 55 PANTHER PTHR46111 RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I
4 55 InterPro IPR008189 rRNA small subunit methyltransferase I
1 60 Gene3D G3DSA:3.40.1010.10 -
1 60 InterPro IPR014777 Tetrapyrrole methylase, subdomain 1
3 53 SUPERFAMILY SSF53790 Tetrapyrrole methylase
3 53 InterPro IPR035996 Tetrapyrrole methylase superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold KP13_01426
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.249

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.12 0.008