Protein profile

KP13_01420

hypothetical protein

Genome: KpKP13

Gene: AHE47412.1 Structure source: AlphaFold + ColabFold UniProt A0A0U2QSC7
Export view
Amino acids 149
Annotations 0
Features 10
PDB binders 0
Druggability 0.275

Overview

Basic information about this protein and its source genome.

Accession
KP13_01420
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47412.1
Status
annotated
Amino acids
149
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
44.068
DEG E-value
1.5700000000000001e-31
Localization
Cytoplasmic
ColabFold pLDDT
85.85

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.275
Structure A0A0U2QSC7
Pocket Pocket 5
P2Rank 0.099
Structure A0A0U2QSC7
Pocket Pocket 1
ColabFold model
FPocket 0.298 · Pocket 2
P2Rank 0.191 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 47 / 4744 genomes with a hit
Normalized 0.01

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
31 148 Pfam PF04002 RadC-like JAB domain
31 148 InterPro IPR025657 RadC-like JAB domain
25 149 Gene3D G3DSA:3.40.140.10 Cytidine Deaminase, domain 2
32 144 CDD cd08071 MPN_DUF2466
32 144 InterPro IPR025657 RadC-like JAB domain
36 117 SUPERFAMILY SSF102712 JAB1/MPN domain
27 149 ProSiteProfiles PS50249 MPN domain profile.
27 149 InterPro IPR037518 MPN domain
10 149 PANTHER PTHR30471 DNA REPAIR PROTEIN RADC
10 149 InterPro IPR001405 Uncharacterised protein family UPF0758

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0U2QSC7
AlphaFold — — full sequence — Viewing
ColabFold KP13_01420
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.275

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.1 0.048
2 2.07 0.046