Target Pathogen

Overview

Basic information about this protein and its source genome.

Accession: KP13_32075
Assembly: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene: AHE47440.1
Status: annotated
Amino acids: 93
Structure source: ColabFold

GO

GO:0000150 Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA. GO:0006310 Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Human identity (%): 0.0
Gut microbiome off-target: hit
Essential (DEG): N
DEG identity (%): 0.0
Localization: Unknown
ColabFold pLDDT: 90.96

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.19

Structure CB_KP13_32075

Pocket Pocket 1

P2Rank

Structure CB_KP13_32075

Pocket No pockets

ColabFold model

FPocket 0.19 · Pocket 1

Core conservation Accessory gene

Roary accessory

CoreCruncher accessory

Gut microbiome 12 / 4744 genomes with a hit

Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3

GO:0000150 Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.
GO:0006310 Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records

Show feature table

Start	End	DB	Term	Name
1	45	ProSiteProfiles	PS51736	Resolvase/invertase-type recombinase catalytic domain profile.
1	45	InterPro	IPR006119	Resolvase, N-terminal catalytic domain
2	46	SUPERFAMILY	SSF53041	Resolvase-like
2	46	InterPro	IPR036162	Resolvase-like, N-terminal catalytic domain superfamily
2	45	Pfam	PF00239	Resolvase, N terminal domain
2	45	InterPro	IPR006119	Resolvase, N-terminal catalytic domain
49	89	SUPERFAMILY	SSF46689	Homeodomain-like
49	89	InterPro	IPR009057	Homeobox-like domain superfamily
47	91	Gene3D	G3DSA:1.10.10.60	-
7	46	Gene3D	G3DSA:6.10.250.10	-
49	89	Pfam	PF02796	Helix-turn-helix domain of resolvase
49	89	InterPro	IPR006120	Resolvase, HTH domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

No pockets are loaded yet for the displayed ColabFold model KP13_32075 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
ColabFold KP13_32075	ColabFold	—	—	full sequence	—	Viewing