Protein profile

KP13_04132

hypothetical protein

Genome: KpKP13

Gene: AHE47481.1 Structure source: AlphaFold + ColabFold UniProt A0A7T7GQY4
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Amino acids 351
Annotations 0
Features 12
PDB binders 0
Druggability 0.912

Overview

Basic information about this protein and its source genome.

Accession
KP13_04132
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47481.1
Status
annotated
Amino acids
351
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
28.313
Human E-value
1.65e-06
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
82.2

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.912
Structure A0A7T7GQY4
Pocket Pocket 1
P2Rank 0.395
Structure A0A7T7GQY4
Pocket Pocket 1
ColabFold model
FPocket 0.251 · Pocket 19
P2Rank 0.602 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 12 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
10 185 SUPERFAMILY SSF53300 vWA-like
10 185 InterPro IPR036465 von Willebrand factor A-like domain superfamily
7 186 Gene3D G3DSA:3.40.50.410 von Willebrand factor, type A domain
7 186 InterPro IPR036465 von Willebrand factor A-like domain superfamily
11 164 Pfam PF00092 von Willebrand factor type A domain
11 164 InterPro IPR002035 von Willebrand factor, type A
10 184 ProSiteProfiles PS50234 VWFA domain profile.
10 184 InterPro IPR002035 von Willebrand factor, type A
8 185 SMART SM00327 VWA_4
8 185 InterPro IPR002035 von Willebrand factor, type A
222 351 Pfam PF15616 TerY-C metal binding domain
222 351 InterPro IPR028274 TerY-C metal binding domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A7T7GQY4
AlphaFold — — full sequence — Viewing
ColabFold KP13_04132
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.912
2 0.558

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 5.14 0.237
2 2.64 0.077
3 2.61 0.075
4 1.61 0.026
5 1.56 0.024