Protein profile

KP13_04140

hypothetical protein

Genome: KpKP13

Gene: AHE47490.1 Structure source: AlphaFold + ColabFold UniProt A0A367TV18
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Amino acids 257
Annotations 1
Features 7
PDB binders 0
Druggability 0.086

Overview

Basic information about this protein and its source genome.

Accession
KP13_04140
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47490.1
Status
annotated
Amino acids
257
Structure source
AlphaFold + ColabFold
GO
GO:0046872 Binding to a metal ion.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
95.92

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.086
Structure A0A367TV18
Pocket Pocket 4
P2Rank 0.93
Structure A0A367TV18
Pocket Pocket 1
ColabFold model
FPocket 0.825 · Pocket 5
P2Rank 0.915 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 17 / 4744 genomes with a hit
Normalized 0.004

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
1 257 PIRSF PIRSF030802 UCP030802
1 257 InterPro IPR024197 Trehalose phosphatase-like
5 234 SUPERFAMILY SSF56784 HAD-like
5 234 InterPro IPR036412 HAD-like superfamily
5 240 CDD cd07520 HAD_like
5 248 Gene3D G3DSA:3.40.50.1000 -
5 248 InterPro IPR023214 HAD superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A367TV18
AlphaFold — — full sequence — Viewing
ColabFold KP13_04140
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 21.51 0.871
2 1.76 0.032