Protein profile

KP13_04144

Tellurium resistance protein terZ

Genome: KpKP13

Gene: AHE47494.1 terZ Structure source: AlphaFold + ColabFold UniProt H6U1W5
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Amino acids 196
Annotations 1
Features 6
PDB binders 0
Druggability 0.216

Overview

Basic information about this protein and its source genome.

Accession
KP13_04144
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47494.1 terZ
Status
annotated
Amino acids
196
Structure source
AlphaFold + ColabFold
GO
GO:0046690 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
82.383
DEG E-value
4.4799999999999996e-111
Localization
Cytoplasmic
ColabFold pLDDT
89.48

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.216
Structure H6U1W5
Pocket Pocket 1
P2Rank 0.048
Structure H6U1W5
Pocket Pocket 1
ColabFold model
FPocket 0.43 · Pocket 1
P2Rank 0.075 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 26 / 4744 genomes with a hit
Normalized 0.005

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0046690 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
5 188 PANTHER PTHR32097 CAMP-BINDING PROTEIN 1-RELATED
4 176 Pfam PF02342 TerD domain
4 176 InterPro IPR003325 TerD domain
21 175 CDD cd06974 TerD_like
21 175 InterPro IPR003325 TerD domain
20 182 Gene3D G3DSA:2.60.60.30 sav2460 like domains

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_H6U1W5
AlphaFold — — full sequence — Viewing
ColabFold KP13_04144
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.216

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.49 0.021