Protein profile

KP13_04145

Tellurium resistance protein terA

Genome: KpKP13

Gene: AHE47495.1 terA Structure source: AlphaFold + ColabFold UniProt A0A4S4SW54
Amino acids 383
Annotations 0
Features 11
PDB binders 0
Druggability 0.604

Overview

Basic information about this protein and its source genome.

Accession
KP13_04145
Gene
AHE47495.1 terA
Status
annotated
Amino acids
383
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
OuterMembrane
ColabFold pLDDT
84.44

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.604
Structure A0A4S4SW54
Pocket Pocket 3
P2Rank 0.067
Structure A0A4S4SW54
Pocket Pocket 1
ColabFold model
FPocket 0.739 · Pocket 6
P2Rank 0.347 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 21 / 4744 genomes with a hit
Normalized 0.004

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
2 312 PANTHER PTHR32097 CAMP-BINDING PROTEIN 1-RELATED
1 383 PIRSF PIRSF037118 TerA
1 383 InterPro IPR017115 Tellurite resistance, TerA
22 160 CDD cd06974 TerD_like
22 160 InterPro IPR003325 TerD domain
205 368 Gene3D G3DSA:2.60.60.30 sav2460 like domains
26 159 Pfam PF02342 TerD domain
26 159 InterPro IPR003325 TerD domain
204 373 CDD cd06974 TerD_like
204 373 InterPro IPR003325 TerD domain
20 157 Gene3D G3DSA:2.60.60.30 sav2460 like domains

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A4S4SW54
AlphaFold full sequence Viewing
ColabFold KP13_04145
ColabFold full sequence Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.604

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.65 0.077
2 1.63 0.026